the lip treatment
treatA real peptide payload in the thing you reapply all day.
12 ml $3.50 per ml
SIZE
30 ml
PROTOCOL
AM/PM
Firmer, bouncier, brighter-looking skin in eight weeks.
$338.40 $376.00 Save $37.60
DO NOT LAYER direct acids
GHK-Cu at 1.0% — the concentration the work is actually done at, not a trace amount with a good story attached. Panthenol and betaine keep it comfortable enough to use morning and night.
It goes on after the water layer, before cream. Not with direct acids: copper peptides and low pH are a standoff, and you paid for the copper.
THE ACTIVE
1%GHK-Cu
with panthenol, betaine
Five flood bands, F-100 to F-500, by how dilute the formula is.
The Copper System only — four SKUs, face only.
What’s inside
The number on the bottle is a position on a scale. This is what sits behind it.
ACTIVE
Copper tripeptide-1 1.0%
A copper-carrying peptide. The most-studied peptide in cosmetic use and the one the range is built around.
SUPPORTING
Pro-vitamin B5
A humectant used for the feel of comfort in a formula that is doing something demanding.
SUPPORTING
Betaine
An osmolyte used to keep an active comfortable on skin.
These are the actives and the supporting ingredients we formulate around. The complete INCI list is being added to every product page.
The difference
Every line below is something you can check on the label or the page before you buy. None of it is a claim about how well the product works.
| What you can verify |
ANNEAL
|
The category |
|---|---|---|
| Every active stated at the percentage it is used at | Yes | Usually a range, or folded into one “complex” |
| A position on one scale, printed on the bottle | Yes | A name and a claim, with no system behind it |
| Layering conflicts printed on the product page | Yes | Rarely mentioned before checkout |
| Volume and price per millilitre both stated | Yes | Volume often left off the label |
| The range is capped at eight and stays eight | Yes | Extended into new SKUs each season |
| No promo code, spend ladder or seasonal sale | Yes | At least one running, most of the year |
Reviews
Unedited, in their words. Every one is tied to a confirmed order, and the four- and five-star ones are not moved to the top.
4.5/5
8 reviews
7 of 8 rated it 4 stars or higher
3 photos from customers
Around week six I thought nothing was happening and then I looked at a photo from January and my cheeks are noticeably firmer. Bouncy is a silly word but it is the accurate one.
Worth it. The bottle lasts about four months for me so the monthly cost is not as frightening as the sticker.
Firmer came later, around week nine.
The texture takes getting used to — it is a proper serum, slightly slippery, and you need to let it sink before anything else goes on or it will pill.
No irritation whatsoever, which surprised me at this concentration. Works alongside my retinal on alternate nights.
That is the entire reason I bought it over three cheaper ones and I do not regret it.
No dramatic before-and-after, just skin that looks better rested than it should.
It is an excellent product and it is a hundred and eighty eight pounds. Both of those are true. I have repurchased once and I am undecided about a third.
No reviews match that filter yet.
The full label, the dose and the price are back at the top of this page.
Questions
Common questions about the blue serum
It is the dose. Every product floods one of five steps of the same blue: the palest is the cleansers, where water does the work, and full-strength cupric is reserved for the four copper products. A product cannot change band because of a season or a repackage.
Because a flagship that can be extended forever is not a flagship. GHK-Cu at full dose is the most expensive thing we make and it stays on the face, in four products. If we launch a fifth copper SKU, we will have changed our minds in public rather than quietly.
On every product, in the first chapter of the page, before any claim is made about it. Where a formula is a blend rather than a single active, the page shows the blend instead of inventing a headline number.
It is printed in the how-to-use block on each product, not buried in an FAQ. The short version: copper peptides and direct acids do not go on together, and a retinal night is followed by SPF in the morning.
The copper protocol — the blue serum, the barrier cream and the daily spf. Treat, repair-adjacent support, and protection, which is the whole argument of the system in three steps.
Before you buy
Every active at the percentage it is used at, and what not to layer it with — stated before any claim is made about it.