the lip treatment
treatA real peptide payload in the thing you reapply all day.
12 ml $3.50 per ml
SIZE
30 ml
PROTOCOL
PM
Calms skin you pushed too far, fast.
$248.40 $276.00 Save $27.60
HEADS UP pause retinals while using
Polynucleotides at 2.0%, with ectoin, panthenol and madecassoside. This is the product for the week after you overdid it, not a permanent fixture.
Nights, and pause retinals while you are using it. Two things competing to resurface the same face is how the week gets worse.
THE ACTIVE
2%polynucleotides
with ectoin, panthenol, madecassoside
Five flood bands, F-100 to F-500, by how dilute the formula is.
Potent non-copper treats, and every SPF.
What’s inside
The number on the bottle is a position on a scale. This is what sits behind it.
ACTIVE
Polynucleotides 2.0%
Long-chain nucleotides used in soothing formulas for skin that has been pushed hard.
SUPPORTING
Madecassoside
A centella-derived ingredient used in soothing formulas.
SUPPORTING
Pro-vitamin B5
A humectant used for the feel of comfort in a formula that is doing something demanding.
SUPPORTING
Ectoin
An extremophile-derived osmolyte used for comfort under environmental stress.
These are the actives and the supporting ingredients we formulate around. The complete INCI list is being added to every product page.
The difference
Every line below is something you can check on the label or the page before you buy. None of it is a claim about how well the product works.
| What you can verify |
ANNEAL
|
The category |
|---|---|---|
| Every active stated at the percentage it is used at | Yes | Usually a range, or folded into one “complex” |
| A position on one scale, printed on the bottle | Yes | A name and a claim, with no system behind it |
| Layering conflicts printed on the product page | Yes | Rarely mentioned before checkout |
| Volume and price per millilitre both stated | Yes | Volume often left off the label |
| The range is capped at eight and stays eight | Yes | Extended into new SKUs each season |
| No promo code, spend ladder or seasonal sale | Yes | At least one running, most of the year |
Reviews
Unedited, in their words. Every one is tied to a confirmed order, and the four- and five-star ones are not moved to the top.
4.6/5
7 reviews
6 of 7 rated it 4 stars or higher
3 photos from customers
What I appreciate most is that the page tells you what polynucleotides actually do rather than implying it is an injectable in a bottle. It is a good soothing repair step and it is honest about being that.
Redness down noticeably by the next morning.
It is the difference between two days of flaking and none.
Texture is a slightly slippery water-gel and it absorbs in about a minute. Layers under everything without pilling. Four stars only because I want a bigger size.
I overdid it with a peel and my face was tight, red and shiny in the bad way. Three nights of this and it had calmed right down. It is expensive and I will keep buying it.
This got me through it without steroids for the first time in about six years.
It works, but I could not tell you it works better than a good ceramide cream for me personally. If your barrier is genuinely damaged I think you will notice more than I did.
No reviews match that filter yet.
The full label, the dose and the price are back at the top of this page.
Questions
Common questions about the recovery ampoule
It is the dose. Every product floods one of five steps of the same blue: the palest is the cleansers, where water does the work, and full-strength cupric is reserved for the four copper products. A product cannot change band because of a season or a repackage.
Because a flagship that can be extended forever is not a flagship. GHK-Cu at full dose is the most expensive thing we make and it stays on the face, in four products. If we launch a fifth copper SKU, we will have changed our minds in public rather than quietly.
On every product, in the first chapter of the page, before any claim is made about it. Where a formula is a blend rather than a single active, the page shows the blend instead of inventing a headline number.
It is printed in the how-to-use block on each product, not buried in an FAQ. The short version: copper peptides and direct acids do not go on together, and a retinal night is followed by SPF in the morning.
The copper protocol — the blue serum, the barrier cream and the daily spf. Treat, repair-adjacent support, and protection, which is the whole argument of the system in three steps.
Before you buy
Every active at the percentage it is used at, and what not to layer it with — stated before any claim is made about it.